New trial from JNJ
Another new, unproven technique to rebuild cartilage is being tested. This one, called CAIS, uses a small piece (biopsy) of a patient's normal appearing cartilage and place it in a matrix- sort of like a jelly- then puts it back into the knee. The cartilage iis "minced" up during the procedure, but not expanded or grown. This is in contract to the ACI approach, which uses tissue culture as a means of expanding the cartilage. It is therefore less expensive. So far only a few patients have trialled this new procedure so it is far too early to tell about uts success.

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http://www.codon.de/_/index.php?CT_cont_id=1_2_0
This German company multiply cell samples and implant them into globdules (anyone thinking of puddy or bubble gum?). According to Wikipedia.org, Co.Don is in the 3rd generation ACI technology. Matrix ACI is second generation.
Here is the actual implantation at a German prviate clinic:
http://www.alphaklinik.com/en/toft/news/cartilage_transplant_state_of_the_art
arthrokinetics is also growing stuff inside a sponge.
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